The Statistics, Epidemiology, and Data Management (SED) Core advances the mission of the HIV Center by serving as a center of excellence for the planning, design, and analysis of investigator-initiated grant-supported studies and behavioral interventions to reduce the risk of HIV infection on the individual, couple, group, institutional, and community levels. The authoritative consultative and educational roles of the SED Core are structured to foster, assure, and implement the highest standards of data quality and effective and efficient data management and analysis for ongoing and future studies.

The SED Core ensures the highest performance of randomized behavioral intervention trials and observational studies by providing HIV Center investigators – both senior scientists and those early in their careers – with a centralized resource for study design and planning; data management, analytic monitoring, and problem resolution; state-of-the-art statistical analysis; and publication preparation.  The Core proactively identifies previously unrecognized design and statistical needs arising in HIV Center studies and to generate innovative design and statistical solutions to these problems. This includes providing support to researchers in designing and conducting interventions and analytic studies that entail consideration of the effects of multiple levels of social organization. 

The SED Core also serves as a forum for the systematic exchange of ideas on methodologic developments in study design and data analysis and on emerging issues in the HIV epidemic worldwide, specifically as they relate to studies of gender, sexuality, and mental health; and through these, to enhance the understanding of HIV Center researchers of statistical, epidemiologic, and data management principles.

The SED Core also interfaces with the Performance, Safety & Monitoring Board (PSMB), participating fully in PSMB meetings, coordinating responses to PSMB queries and recommendations, reviewing the progress of blinded studies in closed session, and serving generally as a liaison between the PSMB and Center investigators in addressing a variety of questions relating to the performance and safety of the Center studies.

Core Members

Bruce Levin, Ph.D.: Core Director (Co-Director for Statistics)
Susie Hoffman, Dr.P.H.: Core Co-Director (Co-Director for Epidemiology)

Howard Andrews, Ph.D.: Core Co-Director (Co-Director for Data Management)
Quarraisha Abdool Karim, Ph.D.
Curtis Dolezal, Ph.D.
Cheng-Shiun Leu, Ph.D.
Denis Nash, Ph.D.
Myunghee C. Paik, Ph.D.

Performance and Safety Monitoring Board Members

Bette Crigger, Ph.D., Chair (Director, Ethics Policy, AMA, Chicago, IL)

Patricia Hawkins, Ph.D. (Whitman-Walker Clinic, Washington, DC)

Don Des Jarlais, Ph.D. (Albert Einstein College of Medicine, New York, NY)

Susan Murphy, Ph.D. (University of Michigan, Ann Arbor, MI)

Nina Regevik, M.D. (Raritan Bay Medical Center, Perth Amboy, NJ)

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