Since our founding in 1987, the HIV Center for Clinical and Behavioral Studies has conducted research on HIV prevention, treatment, and care. In 2023, the HIV Center received its eighth renewal from NIMH to provide support for HIV-related research with the following three primary aims:Advancing our understanding of individual, social, and systemic drivers of the HIV epidemic including mental health and social determinants of health and the development of intervention and implementation science research to achieve local and global EHE goals. Promoting translation of clinical and research findings to prevention and care settings for maximum equitable public health impact. Expanding the cadre of HIV researchers by engaging an inclusive pipeline of emerging investigators through leadership, content, design, and methodological capacity-building.Research associated with the HIV Center comprises approximately 40 individual studies involving more than 100 investigators and staff from disciplines that include psychology, psychiatry, public health, anthropology, sociology, and social work. We work in New York City and State, nationally, and internationally. In all, the HIV Center is one of the oldest and most productive continuously funded AIDS research centers in the United States.