EDUCATION
|
Princeton University, Princeton, New Jersey |
A.B. |
1978 |
Biochemistry |
|
Columbia University, New York, NY |
M.D. |
1982 |
Medicine |
PROFESSIONAL EXPERIENCE
| 1982-1985 |
Pediatric Residency, Joint Program in Primary
Care, Babies Hospital and Harlem Hospital, College of Physicians & Surgeons,
Columbia University, NY |
| 1986 |
Fellowship in General Pediatrics, Harlem
Hospital Center, New York, NY |
| 1986-1987 |
Assistant in Clinical Pediatrics, College of
Physicians & Surgeons, Columbia University, New York, NY |
| 1987 |
Instructor in Clinical Pediatrics, College of
Physicians & Surgeons, Columbia University, NY, NY |
| 1987-1990 |
Asst Clinical Professor of Pediatrics, College
of Physicians & Surgeons, Columbia University, NY, NY |
| 1990-1996 |
Assistant Prof of Clinical Pediatrics, College
of Physicians & Surgeons, Columbia University, NY, NY |
| 1991-present |
Associate Attending Pediatrician, Harlem
Hospital Center, New York, NY |
| 1991-present |
Director, Pediatric HIV Program, Family Care
Center, Harlem Hospital, New York, NY |
| 1996-2003 |
Associate Professor of Clinical Pediatrics, College
of Physicians and Surgeons, Columbia University, New York, NY |
| 2002-2004 |
Deputy Director for Programs, MTCT-Plus Initiative,
Columbia University Mailman School of Public Health, New York, NY |
| 2003-2005 |
Associate Professor of Clinical Pediatrics and
Clinical Epidemiology, Columbia University, New York, NY |
| 2004-present |
Director, MTCT-Plus Initiative, Columbia University
Mailman School of Public Health, New York, NY |
| 2005-present |
Professor of Pediatrics and Epidemiology, College
of Physicians and Surgeons of Columbia University, New York, NY |
HONORS
| 1994-1995 |
Chairperson, New York State Department of Health AIDS
Institute, Committee for the Care of Children and Adolescents with HIV
Infection |
| 1994-1996 |
Member, Pediatric Executive Committee, Pediatric AIDS
Clinical Trials Group |
| 1996 |
Member, Working Group on Antiretroviral Therapy and
Management of HIV-Infected Children |
| 1999 |
Member, Primary Therapy Committee, Pediatric AIDS
Clinical Trials Group, NIH |
| 2000-2002 |
Member, Committee for the Care of Children with HIV,
NYS Department of Health AIDS Institute |
| 2001-present |
Director of Research, Department of Pediatrics, Harlem
Hospital Center, New York |
| 2001 |
Vice Chair, Institutional Review Board, Harlem
Hospital Center, New York |
| 2001-present |
Member, International Research Steering Committee,
Pediatric AIDS Clinical Trials Group, NIH |
| 2001-present |
Member, USPHS Perinatal HIV Guidelines Working Group |
| 2004-present |
Collaborator, Antiretroviral drugs and the Prevention
of Mother-to-Child Transmission of HIV-1 infection in resource-limited
setting, World Health Organization |
| 2006-present |
Chair, Primary Therapy Committee, IMPAACT |
PUBLICATIONS
Heagarty J.D., Abrams E.J., Hutchinson V.E., Nicholas S.W., Suarez M.S., Heagarty
M.C.: The medical care costs of human immunodeficiency virus-infected children
in Harlem. Journal of American Medical Association, 260: 1901-5, 1988.
Rogers M.F., Ou C., Rayfield M., Thomas P.A., Schoenbaum E.E., Abrams E.,
Krasinski K., Selwin P.A., Moore J., Kaul A., Grimm K.T., Bamji M., Schochetman
G., and the New York City Collaborative Studie of Maternal HIV Transmission and
Montefiore Medical Center HIV Perinatal Transmission Study Group.: Use of the
Polymerase Chain Reaction for early detection of the proviral sequences of human
immunodeficiency virus in infants born to seropositive mothers. New England
Journal of Medicine, 320: 1649-54, 1989.
Just J., Louis L., Abrams E., Nicholas S.W., Wara D., Stein Z., King M.C.:
Genetic risk factors for perinatally acquired HIV infection. Pediatric and
Perinatal Epidemiology, 6: 215-24, 1992.
Jones D.S., Abrams E., Ou C., Nesheim S., Conner E., Davenny K., Thomas P.,
Sawyer M., Krasinski K., Bamji M., Rapier J., Kilbourne B., Rogers M.: Lack of
detectable human immunodeficiency virus infection in antibody-negative children
born to human immunodeficiency virus-infected mother. Pediatric Infectious
Diseases Journal, 12:222-7, 1993.
Spector S.A., Gelber R.D., McGrath N., Wara D., Barzilai A., Abrams E., Bryson
Y.J., Dankner W.M., Livingston R.A., Connor E.M., The Pediatric AIDS Clinical
Trials Group: A controlled trial of intravenous immune globulin for the
prevention of serious bacterial infections in children receiving zidovudine for
advanced human immunodeficiency virus infection. New England Journal of
Medicine, 331:1181-7, 1994.
Abrams E.J., Matheson P.B., Thomas P.A., Thea D.M., Krasinski K., Lambert G.,
Shaffer N., Bamji M., Hutson D., Grimm K., Kaul A., Bateman D., Rogers M., The
NYC Perinatal HIV Transmission Collaborative Study Group: Neonatal predictors of
infection status and early death among 332 infants at risk of HIV-1 infection
monitored prospectively from birth. Pediatrics, 96:451-8, 1995.
Matheson P.B., Abrams E.J., Thomas P.A., Hernan M.A., Thea D.M., Lambert G.,
Krasinski K., Bamji M., Rogers M.F., Heagarty M., The New York City Perinatal
HIV Transmission Collaborative Study Group. Efficacy of antenatal zidovudine in
reducing perinatal transmission of human immunodeficiency virus type 1. Journal
of Infectious Diseases, 172:353-8, 1995.
Just J.J., Abrams E., Louie L.G., Urbano R., Wara D., Nicholas S.W., Stein Z.,
King M.C.: Influence of host genotype on progression to acquired
immunodeficiency syndrome among children infected with human immunodeficiency
virus type 1. Journal of Pediatrics, 127:544-9, 1995.
Abrams E.J., Bateman D.A.: Voluntary newborn HIV-1 antibody testing: a
successful model program for the identification of HIV-1-seropositive infants.
Bulletin of the New York Academy of Medicine: A Journal of Urban Health, 72:
443-453, 1995.
Thea D., Lambert G., Weedon J., Matheson P.B., Abrams E.J., Bamji M., Straus W.L.,
Thomas P.A., Krasinski K., Heagarty M., The New York City Perinatal HIV
Transmission Collaborative Study Group: Benefit of primary prophylaxis before 18
months of age in reducing the incidence of pneumocystis carinii pneumonia and
early death in a cohort of 112 HIV-infected infants. Pediatrics, 97: 59-64,
1996.
Tetali S., Abrams E., Bakshi S., Paul M., Oyaizu N., Pahwa S.: Virus load as a
marker of disease progression in HIV-infected children. AIDS Research and Human
Retroviruses, 12:669-75, 1996.
Steketee R.W., Abrams E.J., Thea D.M., Brown T.M., Lambert G., Orloff S.,
Matheson P.B., Bamji M., Schoenbaum E.A., Thomas P.A., Rapier J., Kalish M.L.,
The NYC Perinatal HIV Transmission Collaborative Study: Early detection of
perinatal human immunodeficiency virus type-1 infection using HIV RNA
amplification and detection. Journal of Infectious Diseases, 175: 707-711, 1997.
Kuhn L., Abrams E.J., Matheson P.B., Thomas P.A., Lambert G., Bamji M.,
Greenberg B., Steketee R.W., Thea D.M., The New York City Perinatal HIV
Transmission Collaborative Study Group: Timing of maternal-infant HIV
transmission associations between intrapartum factors and early polymerase chain
reaction results, AIDS, 11:429-435, 1997.
Thea D.M., Steketee R.W., Pliner V., Bornschlegel K., Brown T., Orloff S.,
Matheson P.B., Abrams E.J., Bamji M., Lambert G., Schoenbaum E.A., Thomas P.A.,
Heagarty M., Kalish M.L., The New York City Perinatal Transmission of HIV-1: The
effect of maternal viral load on the risk of perinatal transmission of HIV-1.
AIDS, 11:437-444, 1997.
Englund J.A., Baker C.J., Raskino C., McKinney R.E., Petrie B., Fowler M.G.,
Pearson D., Gershon A., McSherry G.D., Abrams E.J., Schliozberg J., Sullivan J.L.,
for the AIDS Clinical Trials Group (ACTG) Study 152 Team: Zidovudine, Didanosine,
or both as the initial treatment for symptomatic HIV-infected children. New
England Journal of Medicine, 336:1704-12, 1997.
Rousseau C., Abrams E.J., Lee M., Urbano R., King M.C.: Long terminal repeat and
nef gene variants of human immunodeficiency virus type 1 in perinatally infected
long term survivors and rapid progressors. AIDS Resources of Human Retroviruses,
13:1611-1623, 1997.
Abrams E.J., Weedon J., Stekette R.W., Bamji M., Brown T., Kalish M.L., Lambert
G., Schoenbaun E.A., Thomas P.A., Thea D.M., The New York City Perinatal HIV
Transmission Collaborative Study Group: Association of HIV viral load early in
life with disease progression among HIV-infected infants. Journal of Infectious
Diseases, 178:101-108, 1998.
Simonds R.J., Steketee R., Nesheim S., Matheson P., Palumbo P., Alger L., Abrams
E.J., Orloff S., Lindsay M., Bardeguez A.D., Vink P., Byers R., Rogers M., for
the Perinatal AIDS Collaborative Transmission Studies (PACTS): Impact of
Zidovudine use on risk and risk factors for perinatal transmission of HIV. AIDS,
12:301-308, 1998.
Kuhn L., Steketee R.W., Weedon J., Abrams E.J., Lambert G., Bamji M., Schoenbaum
E., Farley J., Nesheim S., Palumbo P., Simonds R.J., Thea D., for the Perinatal
AIDS Collaborative Transmission Study (PACTS). Distinct risk factors for
intrauterine and intrapartum HIV transmission and consequences for disease
progression in infected children. Journal of Infectious Diseases, 179:52-8,
1999.
Kuhn L., Abrams E.J., Weedon J., Lambert G., Schoenbaum E.E., Nesheim S.R.,
Palumbo P., Vink P.E., Bulterys M for the Perinatal AIDS Collaborative
Transmission Study: Disease progression and early viral dynamics in HIV-infected
children exposed to zidovudine during prenatal and perinatal periods. Journal of
Infectious Diseases, 182:104-111, 2000.
Abrams E.J., Thomas P., Weedon J., Bertolli J., Bornschegle K., Cervia J.,
Lamberg G., Mendez H., Singh, T., for the New York City Pediatric Spectrum of
Disease Consortium. Aging cohort of HIV-infected children in New York City.
Pediatric Infectious Diseases Journal, 20:511-7, 2001.
Ioannidis J., Abrams E.J., Ammann A., Bulterys M., Goedert J.J., Gray L., Korber
B.T., Mayaux M.J., Mofenson L.M., Newell M-L., Shapiro D.E., Teglas J.P.,
Wilfert C.M.: Perinatal transmission of HIV-1 from pregnant women with RNA viral
load less than 1000 copies/ml. Journal of Infectious Diseases, 183: 539-545,
2001.
Mellins C.A., Brackis-Cott E., Dolezal C., Richards A., Nicholas S., Abrams E.J.:
Patterns of HIV status disclosure to perinatally infected HIV-positive children
and subsequent mental health outcomes. Clinical Child Psychology and Psychiatry,
7: 101-114, 2001.
Abrams, E.J., Wiener, J., Carter, R., Kuhn, L., Palumbo, P., Nesheim, S., Lee,
F., Vink, P., Marc Bulterys for the Perinatal AIDS Collaborative Transmission
Study (PACTS) Group: Maternal health factors and early pediatric antiretroviral
therapy influence the rate of perinatal HIV-1 disease progression in children.
AIDS, 17(6):867-877, 2003.
Kuhn, L., Abrams, E.J., Palumbo, P., Bulterys, M., Aga, R., Louie, L., and
Hodge, T. for Perinatal AIDS Collaborative Transmission Study (PACTS): Maternal
versus paternal inheritance of HLA class I alleles among HIV-infected children:
consequences for clinical disease progression. AIDS, 18:1281-1289, 2004.
Chiriboga, C.A., Fleishman, S.A., Champion, S.A., Robinson, L.G., and Abrams,
E.J. : The changing face of HIV encephalopathy in the era of highly active
antiretroviral therapy (HAART): incidence and cumulative prevalence among
children with established HIV infection. Journal of Pediatrics, 146(3):402-407,
2005.
Weidle, P.J., Abrams, E.J., Gvetadze, R., Rivadeneira, E., and Kline, M.:
Comparison of pediatric drug dosing for zidovudine an didanosine form a chart
based on weight (kg) dosing recommendations to dosing determine body
body-surface area. Pediatric Infectious Diseases Journal, 25:59-64, 2006.
Mellins, C.A., Brackis-Cott, E., Dolezal, C., and Abrams, E.J.: Psychiatric
Disorders in Youth with Perinatal HIV Infection. Pediatric Infectious Diseases
Journal, 25:432-437, 2006. |
