 Dr. El-Sadr has led the Division of
Infectious Diseases at Harlem Hospital for two decades, where she was
instrumental in the development of an internationally recognized comprehensive
HIV/AIDS and TB program focused on service, training and research. She has been
the principal investigator of large number of grants funded through NIH, CDC,
HRSA, New York State and New York City Departments of Health and was
instrumental in furthering the understanding of the epidemiology of HIV and TB
as well as to the identification of effective strategies for their prevention
and treatment.Since joining Mailman School of Public Health, Dr. El-Sadr
established the Center for Infectious Diseases Epidemiologic Research (CIDER)
to enhance the training and research opportunities in this discipline. She is
principal investigator for several NIH-funded therapeutic and prevention
research grants and leads several CDC-funded TB grants. She established a
Domestic Prevention Working Group within the HIV Prevention Network in order to
focus on domestic aspects of the HIV epidemic. Dr. El-Sadr also established and
directs the International Center for AIDS Care and Treatment Programs (ICAP), a
large center with more than 400 staff around the world. ICAP provides technical
assistance in resource-limited countries for programs that focus on HIV
prevention, care and treatment as well as related conditions. She also serves
on several US and international committees. Her interests include program
development, establishing systems that support high quality programs and
contribution to the knowledge base in infectious diseases and other health
threats that affect vulnerable communities in the US and internationally.
EDUCATION
|
Cairo University, Faculty of Medicine, Cairo, Egypt |
M.D.
|
1974
|
Medicine |
| Columbia University, New York, NY
|
M.P.H. |
1991 |
Epidemiology |
| Harvard University, Cambridge, MA |
M.P.A. |
1996
|
Public Administration |
PROFESSIONAL EXPERIENCE
| 1975-1976 |
Rotating Resident, Cairo University Hospitals,
Cairo, Egypt |
| 1976-1979 |
Intern and Resident, Cabrini Medical Center, New
York Medical College, Internal Medicine, New York, NY |
| 1979-1980 |
Fellow, New York Veterans Administration Medical
Center, Infectious Disease Section, New York, NY |
| 1980-1982 |
Division of Geographic Medicine, Case Western
Reserve University, Cleveland, OH |
| 1988-present |
Director, Division of Infectious Diseases, Harlem
Hospital Center, New York, NY |
|
1988-present |
Professor of Clinical Medicine, Columbia
University College of Physicians and Surgeons, New York, NY |
| 1999-present |
Director, Center for Infectious Disease
Epidemiologic Research, Department of Epidemiology, Mailman School of Public
Health, Columbia University, New York, NY |
| 2000-present |
Professor of Clinical Epidemiology, Mailman School
of Public Health, Columbia University, New York, NY |
| 2001-present |
Director, Center for Infectious Diseases
Epidemiologic Research (CIDER), Columbia Mailman School of Public Health, New
York, NY |
| 2004-present |
Director, International Center for AIDS Care and
Treatment Programs, Columbia University, Mailman School of Public Health, New
York, NY |
| 2004-present |
Director, International Center for AIDS Care and
Treatment Programs (ICAP), Columbia Mailman School of Public Health, New York,
NY |
HONORS
| 1994-present |
Co-chair, Steering Committee, Community Program for Clinical
Research on AIDS, National Institutes of Allergy and Infectious
Diseases |
| 1994-2004 |
Board Member, American Foundation for AIDS Research (AmFAR) |
| 1994-1997 |
Chair, Tuberculosis Committee, Infectious Diseases Society of
America |
| 1996-1999 |
Member, Antiviral Advisory Committee, Food and Drug Administration |
| 1997-2003 |
Member, Advisory Council for the Elimination of TB, CDC, HHS |
PUBLICATIONS
Gollub, E., Stein, Z., and El-Sadr, W.: A short term acceptability of the
Reality female condom among
women living or working in Harlem, New York City. Family Planing Perspectives,
27:155-158, 1995.
Ehrhardt, A.A., Nostlinger, C., Meyer-Bahlburg, H., Exner, T., Gruen, R.,
Yingling, S., Gorman, J., El-Sadr, W., and Sorrel, S.: Sexual risk behavior
among women with injected drug use histories. J Psychol Hum Sex, 7:99-119,
1995.
El-Sadr, W., Medard, F., and Berthaud, V.: Directly observed therapy for
tuberculosis: The Harlem experience. Am Public Health J, 86:1146-1149, 1996.
Gordin, F., Matts, J.P., Miller, C., Brown, L.S., Hafner, R., John, S.L.,
Klein, M., Vaughn A., Besch C.L., Perez, G., Szabo, S., and El-Sadr, W.: A
controlled trial of Isoniazid in persons with anergy and human immunodeficiency
virus infection who are at high risk for tuberculosis. N Engl J Med,
337:315-320, 1997.
Schuman, P., Capps, L., Peng, G., Vazquez, J., El-Sadr, W., et al.: Weekly
Fluconazole for the prevention of mucosal candidiasis in women with HIV. Ann
Int Med, 126:689-696, 1997.
Capps, L., Peng, G., Doyle, M., El-Sadr, W., and Neaton, J.: Sexually
transmitted diseases in women infected with the human immunodeficiency virus.
STDs, 25:443-447, 1998.
El-Sadr, W., Murphy, R., Yurik, T., et al.: Atovaquone compared with dapsone
for the prevention of Pneumocystis carinii pneumonia in patients with HIV
infection who cannot tolerate Trimethoprim, sulfonamides or both. N Engl J Med,
339:1889-1895, 1998.
Cohn, D.L., Fisher, E.J., Peng, G.T., Hodges, J.S., Chesnut, J., Child,
C.C., Franchino, B., Gilbert, C.L., El-Sadr W, et al.: A prospective randomized
trial of four three-drug regimens in the treatment of disseminated
Mycobacterium avium complex disease in AIDS patients: Excess mortality
associated with high dose clarithromycin. Clin Infect Dis, 29:125-133, 1999.
El-Sadr, W., Luskin-Hawk, R., McCabe Yurik, T., et al.: A randomized trial
of daily and thrice weekly trimethoprim- sulfamethoxazole for the prevention of
Pneumocystis carinii pneumonia in HIV-infected individuals. Clin Infect Dis,
29:755-783, 1999.
Stein, Z., Saez, H., El-Sadr, W., et al.: Safer sex strategies for women:
The hierarchical model in methadone treatment clinics. J Urban Health; Bulletin
of the New York Academy of Medicine, 75:62-72, 1999.
El-Sadr, W.M., Perlman, D.C., Denning, E., Matts, J.P., Cohn, D.L.: A review
of efficacy studies of 6-month short-course therapy for tuberculosis among
patients infected with human immunodeficiency virus: Differences in study
outcomes. Clin Infect Dis, 32:623-632, 2001.
El-Sadr, W.M., Burman, W.J., Grant, L.B., et al.: Discontinuation of
prophylaxis for mycobacterium avium complex disease in HIV-infected patients
who experience CD4 cell response on antiretroviral therapy: Results of a
randomized placebo-controlled multicenter trial. N Engl J Med, 342:1085-1092,
2001.
Rabkin, M., El-Sadr, W., Katzenstein, D.A., et al.: Antiretroviral treatment
in resource-poor settings: Clinical research priorities. Lancet, 360:1503-1505,
2002.
Friis-Moller, N., Weber, R., Reiss, P., Thiebaut, R., Kirk, O., d'Arminio
Monforte, A., Pradier, C., Morfeldt, L., Mateu, S., Law, M., El-Sadr, W., and
DAD study group. Cardiovascular disease risk factors in HIV
patients--association with antiretroviral therapy: Results from the DAD study.
AIDS, 17:1179-1193, 2003.
Friedland, G., Abdool Karim, S., Abdool Karim, Q., Jack, C., Gandhi, N., and
El-Sadr, W.: Utility of tuberculosis directly observed therapy programs as
sites for access to and provision of antiretroviral therapy in resource-limited
countries. Clin Infect Dis, 38:S421-8, 2004.
Landon, M., and El-Sadr, W.: Expanding access to antiretroviral therapy
through the public sector—the challenge of retaining patients in long-term
care. S Afr Med J, 94:273-274, 2004.
Salazar-Schicchi, J., Jedlovsky, V., Ajayi, A., Colson, P.W.,
Hirsch-Moverman, Y., and El-Sadr, W.: Physician attitudes toward Bacille
Calmette Guerin vaccination and treatment of latent tuberculosis infection
treatment. Int J Tuberc Lung Dis, 8:1443-1447, 2004.
Absalon, J., Della-Latta, P., Wu, F., and El-Sadr, W.M.: Sexual behaviors
and condom use of HIV infected men and women of color attending a treatment and
care clinic. J Nat Med Ass, 97:25S-31S,
2005.
El-Sadr, W.M., Mullin, C.M., Carr, A., Gibert, C., Rappoport, C.,
Visnegarwala, F., Grunfeld, C., and Raghavan, S.S.: Effects of HIV disease on
lipids, glucose and insulin levels: Results from a large antiretroviral naïve
cohort. HIV Med, 6:1-7, 2005.
Myer, L., Morroni, C., and El-Sadr, W.M.: Reproductive decisions in
HIV-infected individuals. Lancet, 366:698-700, 2005.
Myer, L., Rabkin, M., Abrams, E.J., Rosenfield, A., and El-Sadr, W.M.: Focus
on women: Linking HIV care and treatment with reproductive health services in
the MTCT-Plus Initiative. Reproductive Health Matters, 13:136-146, 2005.
Shlay, J.C., Visnegarwala, F., Bartsch, G., Wang, J., Peng, G., El-Sadr, W.,
Givert, C., Kotler, D., Grunfeld, C., and Raghavan, S.: Body composition and
metabolic changes in antiretroviral naïve patients randomized to didanosine and
stavudine vs. abacavir and lamivudine. J Acquir Immune Defic Syndr, 38:147-155,
2005.
Thiebaut, R., El-Sadr, W.M., Friis-Moller, N., Rickenbach, M., Reiss, P.,
Arinio Monforte, A., Morfeldt, L., Fontas, E., Kirk, O., De Wit, S., Calvo, G.,
Law, M., Cabis, F., Sabin C., and Lundgren, J., and the DAD Study Group:
Predictors of hypertension and changes of blood pressure in HIV-infected
patients. Antiviral Therapy, 10:811-823, 2005.
Visnegarwala, F., Raghavan, S.S., Mullin, C.M., Bartsch, G., Wang, J.,
Kotler, D., Gibert, C.L., Shlay, J., Grunfeld, C., Carr, A., and El-Sadr, W.M.:
Sex differences in the associations of HIV disease characteristics and body
composition in antiretroviral-naïve persons. Am J Clin Nutr, 82:850-856, 2005.
Burman, W., Benator, D., Vernon, A., Khan, A., Jones, C., Siva, C., Lahart,
C., Weis, S., King, B., Manura, B., Weiner, M., and El-Sadr, W.M.: Acquired
Rifamycin-resistance with twice-weekly treatment of HIV-related Tuberculosis.
Am J Respir Crit Care Med, 173:350-356, 2006.
El-Sadr, W.M., Lundgren, J.D., Neaton, J.D., Gordin, F., Abrams, D.,
Babiker, A., Clumeck, N., Cohen, C.J., Cohn, D., Cooper, D., Emery, S.,
Fatkenheuer, G., Gazzard, B., Grund, B., Hoy, J., Klingman, K., Losso, M.,
Ramos, J.M., Markowitz, N., Neuhaus, J., Phillips, A., and Rappoport, C.: CD4+
Count-Guided Interruption of Antiretroviral Treatment: The Strategies for
Management of Antiretroviral Therapy (SMART) Study Group. New Engl J Med,
355:22, 2283-96, 2006.
El-Sadr, W.M., Mayer, K.H., Maslnakowski, L., Hoesley, C., Justman, J., Gai,
F., Mauck, C., Absalon, J., Morrow, K., Masse, B., Soto-Torres, L., Kwiecien,
A.: Safety and acceptability of cellulose sulfate as a vaginal microbicide in
HIV-infected women. AIDS, 20:1109-1116, 2006.
Tsiouris, S.J., Austin, J., Toro, P., Coetzee, D., Weyer, K., Stein, Z., and
El-Sadr, W.M.: Results of a tuberculosis-specific IFN-gamma assay in children
at high risk for tuberculosis infection. Int J Tuberc Lung Dis, 10:939-941,
2006.
Tsiouris, S.J., Coetzee, D., Toro, P.L., Austin, J., Stein, Z., and El-Sadr,
W.M.: Sensitivity analysis and potential uses of a novel gamma interferon
release assay for diagnosis of tuberculosis. J Clin Micro, 44:2844-2850, 2006.
Sarmiento, K., Hirsch-Moverman, Y., Colson, P.W., and El-Sadr, W.M.:
Help-seeking behavior of marginalized groups: a study of TB patients in Harlem,
New York. Int J Tuberc Lung Dis, 10:1-6, 2006. |
