MEDICAL ADHERENCE AND COPING WITH THE CONSEQUENCES OF HIV INFECTION

Grant Title: Developing an HIV Adherence and Sexual Risk Reduction Intervention in the Dominican Republic

Funding Source and Period: HIV Center Pilot Studies Program; 2006-2007

Key HIV Personnel

Investigators: Robert Remien, Ph.D., Alan Berkman, M.D.

Project Overview
(from abstract of research plan)

The goal of this study is to gather formative and feasibility data for the development of a behavioral intervention addressing medication adherence and sexual risk behaviors among HIV+ patients on antiretroviral therapy in the Dominican Republic's National Treatment Program (NTP). The study will be done in partnership with the Dominican Directorate of STI and HIV Control [DIGECITSS] and will utilize both quantitative and qualitative methodologies to (1) assess the perceived need and willingness to participate in such an intervention among patients, clinical staff, administrators and community based organization; (2) to determine optimal modes of intervention delivery, and (3) to gather information on sexual risk behaviors and challenges to adherence from patients to inform the development of an appropriately tailored intervention. Data will be gathered from three established clinical sites that are characteristic of the range of treatment venues in the Dominican Republic, including both rural and urban sites and public and NGO-operated sites. This proposal draws on successful behavioral interventions developed and tested by Dr. Remien (PI) and on the close collaborative relationships in the Dominican Republic developed over the past three years by Dr. Berkman (Co-PI). Results from this preliminary study will be used to develop the intervention curriculum and inform the writing of an R34 application to the National Institute of Mental Health. This will be the first theory-based adherence/risk reduction intervention targeted to the Spanish-speaking people of the Caribbean area and will be adopted by the Dominican NTP if proven to be efficacious.

Update: 5/17/07