The fourth phase of the epidemic has focused on US and global EHE initiatives and can be seen as a critical moment – a tipping point – if all evidence-based tools can be adopted and brought to scale. Realizing this goal requires interdisciplinary research, particularly integration of biomedical with behavioral and social sciences. Further, the critical persistently high-risk populations most likely to have co-morbidities and face other intersecting gender, sexual, racial/ethnic, economic challenges must be engaged and supported along the HIV prevention and treatment continua.
The HIV Center’s research – conducted in New York City, New York State, and countries hardest hit by the HIV/AIDS epidemic – is focused on the following major areas:
The HIV Center has been awarded 9 administrative supplements in support of the Ending the HIV Epidemic: A Plan for America (EHE) initiative. These implementation science research projects were developed by our teams of ARC investigators and community and local partners to support the local ending the HIV epidemic plans. Our investigators have also coordinated with local EHE teams to ensure the projects support and inform local EHE plans.
Social Determinants of HIV Risk and Prevention
Impact of social cohesion and social capital in PrEP uptake and adherence among transwomen of color (R01MD013554)
PrEP uptake and adherence among young Black MSM: Neighborhood and network determinants (R01MH112406)
Developing a gender-enhanced PrEP information-motivation workshop for young South African women (R34MH115781)
Social environmental drivers of stimulant use and its impact on HIV prevention and treatment in Black MSM (R21DA053156)
Effects of overlapping pandemics on coping and behavioral health among young adults affected by HIV (R21MH130268)
Mitigating sexual stigma within healthcare interactions to improve engagement of MSM in HIV prevention (K23MH124569)
Suubi(Hope)4StrongerFamilies: Addressing child behavioral health by strengthening financial stability and parenting among families in Uganda (R01MH128905)
PI: Fred Ssewamala, PhD
In-depth understanding of HIV risk behavior among MSM in Sub-Saharan Africa (R21MH130217)
HIV Health Outcomes and Engagement in Care and Treatment
Characterizing sleep, ART adherence and viral suppression among Black sexual minority men (R01HL160325)
Intervening to improve HIV treatment and reduce drinking in young Black MSM (K01AA028199)
Suubi+Adherence-R2: Examining longitudinal HIV treatment adherence among youth living with HIV (YLHIV) transitioning into young adulthood (R01HD074949)
PI: Fred Ssewamala, PhD
A Combination Intervention Strategy to Improve Health Outcomes for Adolescents Living with HIV in Mozambique (UG3HD096926)
Strengthening the safety net: Testing a novel Data-to-Suppression (D2S) intervention strategy in the Ryan White HIV/AIDS Program (R01MH125735)
Atlanta MACS/WIHS Combined Cohort Study Clinical Research Site (U01HL146241)
Mentoring Research in Non-infectious Complications of HIV (K24AI155230)
Oral immune activation and alveolar bone loss in HIV-infected postmenopausal women (R01DE026924)
Mental Health and Substance Use in the Context of HIV
Cannabis use, PrEP and HIV transmission risk among Black MSM in Chicago (R01DA054553)
Health and justice: A continuum of care for HIV and SU for justice-involved youth (R01DA043122)
Facilitating Opioid Care Connections: System level strategies to improve use of MAT and movement through the opioid care cascade for defendants in a new Opioid Court system (UG1DA050071)
Intervening to improve HIV treatment and reduce drinking in young Black MSM (K01AA028199)
Effects of overlapping pandemics on coping and behavioral health in young adults affected by HIV (R21MH130268)
Pathways to successful aging among perinatally HIV-infected and exposed young adults: Risk, resilience, and the role of perinatal HIV infection (CASAH 4) (R01MH69133)
Denis Nash, PhD and Kathryn M. Anastos, MD
Central Africa International Epidemiologic Database to Evaluate AIDS (leDEA-CA) (U01AI096299)
NIDA Clinical Trials Network: New York Node (UG1DA013035)
Evaluating implementation strategies of behavioral health integration into HIV prevention and care including telehealth (P30MH043520-32S2)
Enhancing research for inflammation and cognitive health in perinatally acquired HIV (R21TW011683)
Milton Wainberg, MD and Annette Sohn, MD
Capacity development for HIV and mental health research in Asia (D43TW011302)
Uptake of Emerging Biomedical Technologies
A multilevel, multicomponent intervention to increase uptake of HIV testing and biomedical HIV prevention among African-American/Black gay, bisexual and same-gender loving men (R01MH129198)
Perceptions and preferences around long-acting injectables in the Ryan White HIV/AIDS Program (R34MH126809)
Developing tailored delivery and adherence interventions for use of long-acting biomedical HIV prevention strategies by transgender women (K01MH115785)
Robert H. Remien, PhD and Catherine Orrell, MBChB, MMed, MSc
Use of ARV drug levels in DBS to assess and manage ART adherence in South Africa (R01AI122300)
Designing differentiated PrEP service delivery models for implementation in New York City emergency departments through a community collaborative (P30MH043520-33S2)
Digital, Telehealth, and Big Data Strategies
Leveraging social networks to increase COVID-19 testing uptake: A comparison of credible messenger and chain referral recruitment approaches (UG1DA050071)
Using mobile technology to prevent HIV and related youth health problems: sexual health, mental health, and substance use in Uganda (K01MH122319)
Social media campaign to increase PrEP engagement among young Latinx and Black MSM (P30MH043520-32S1)
Improving assessment for neurocognitive impairment in perinatally HIV-infected youth (R01HD095256)
Enhancing research for inflammation and cognitive health in perinatally acquired HIV (R21TW011683)
Building resources to assess impaired neurocognition in children with HIV in LMICs (R21TW012104)
EHE Administrative Supplements
Implementing Integrative HIV-Serious Mental Illness Case Management to Reduce HIV-related Health Disparities (P30MH43520-34W1)
Implementation Mapping to Promote HIV Self-Testing and Linkage to HIV Prevention, Care, and Social Services among New Yorkers of Trans Experience (P30MH43520-34W2)
Ending the HIV Epidemic through stigma-reduction: Applying "Getting-To-Outcomes' in a Ryan White Healthcare Site (P30MH043520-33S1)
Designing Differentiated PrEP Service Delivery Models for Implementation in New York City Emergency Departments through a Community Collaborative (P30MH043520-33S2)
Using A Social Media Campaign to Increase PrEP Engagement among Young Latinx and Black Men who Have Sex with Men (P30MH043520-32S1)
Evaluating Implementation Strategies of Behavioral Health Integration into HIV Prevention and Care including Telehealth (P30MH043520-32S2)
Building a coalition to overcome intersecting stigmas and improve HIV prevention, care access, and health outcomes in New York City (P30MH043520-31S1)
Integrating behavioral health into HIV prevention and care: Transforming practice to End the Epidemic (P30MH043520-31S2)
Matthew Feldman, PhD, MSW and Claude Ann Mellins, PhD
Ending the Epidemic for young adults living with HIV: Leveraging Ryan White Part A services to improve health outcomes (P30MH043520-31S3)
