Nash iedea-ca

IeDEA-CA: Central Africa International Epidemiologic Database to Evaluate AIDS

Principal Investigator: 

Kathryn Anastos, MD

Denis Nash PhD, MPH

Co-Investigator(s):

Adebola Ademeiji PhD, MPH, MsC, MBA  
Phuilip Castle PhD, MPH  
Mark Kuniholm, PhD, MS   
Don Hoover, PhD, MPH  
Stephany Duda PhD, MS    
Batya Elul, PhD, MsC   
April Kimmel, PhD, MS   
Qiuhu Shi, PhD, MS   
Marcel Yotebieng, MD, MPH, PhD  
Eugene Mutimura, MsC, PhD   
Anastase Dzudie, MD, PhD   
Jean d’amour Sinayobye, MD, MsC  
Heidi Jones, PhD, MPH   
Elizabeth Kelvin, PhD, MPH  
Theodore Niyongabo, MD  
Cristella Twizere, MD

Funding Agency:

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborating Institution: 

Centre National de Reference en Matière de VIH/SIDA (Burundi);  
Kinshasa School of Public Health and Kalembelembe Pediatric Hospital (DRC)  
Centre de Traitement Ambulatoire de Pointe Noire   
Centre de Traitement Ambulatoire de Brazzaville (Republic of Congo)  
Research for Development International (Cameroon)  
Rwanda Military Hospital   
Data Solutions LLC  
Vanderbilt University   
Columbia University  
Ohio State University  
Virginia Commonwealth University

Study Location:

Burundi, Cameroon, the Democratic Republic of Congo (DRC), and Rwanda

Description:

The IeDEA-CA network includes 15 partners in Burundi, Cameroon, the Democratic Republic of Congo (DRC), and Rwanda, who are utilizing implementation science to identify effective strategies for optimizing HIV care outcomes, including timely diagnosis and care enrollment, care retention, ART initiation and viral suppression.  IeDEA-CA partners are also conducting clinical epidemiologic investigations of co-morbidities of aging among HIV+ persons and they are engaged in translational work to explore extreme clinical phenotypes of HIV infection, such as elite suppressors, long-term non-progressors, and poor responders to ART.  IeDEA-CA also leads and contributes to multi-regional IeDEA projects,and maintains updated population-based data from various sources for use in examining contextual determinants of HIV outcomes

Presentations/  
Publications:  
 

• Dusingize JC, Hoover DR, Shi Q, Mutimura E, Kiefer E, Anastos K. Associations of HIV infection with insulin and glucose levels in antiretroviral-naive Rwandan women: a cross-sectional analysis. BMJ Open. 2013 Dec 5;3(12): e003879.
• Kimmel AD, Nash D. (2017). HIV prevention resources: time to move toward affordability. Lancet HIV. 4(5):e191-e193
• Yotebieng M, Moracco KE, Thirumurthy H, Edmonds A, Tabala M, Kawende B, Wenzi LK, Okitolonda EW, Behets F. (2017). Conditional Cash Transfers Improve Retention in PMTCT Services by Mitigating the Negative Effect of Not Having Money to Come to the Clinic. J Acquir Immune Defic Syndr. 2017 Feb 1;74(2):150-157.
• Hu Y, Hoover DR. (2016). Non-randomized and randomized stepped-wedge designs using an orthogonalized least squares framework. Stat Methods Med Res. First Published July 10, 2016
• Yotebieng, Marcel, et al. (2016). Conditional cash transfers to increase retention in PMTCT care, antiretroviral adherence, and postpartum virological suppression: A randomized controlled trial. Journal of Acquired Immune Deficiency Syndromes 72.Suppl 2 (2016): S124.
• Freeman E, Semeere A, Wenger M, et al. (2016). Pitfalls of practicing cancer epidemiology in resource-limited settings: the case of survival and loss to follow-up after a diagnosis of Kaposi’s sarcoma in five countries across sub-Saharan Africa. BMC Cancer, 16:65.
• Yotebieng M, Tabala M, Batumbula ML, et al. (2016). Impact of WHO 2010 Guidelines on Antiretroviral Therapy Initiation among Patients with HIV-Associated Tuberculosis in Clinics with and without Onsite HIV Services in the Democratic Republic of Congo. Tuberculosis Research and Treatment. 2016;2016:1027570. 
• Yotebieng M, Edmonds A, Lelo P, et al. (2015). High completion of Isoniazid Preventive Therapy among HIV-infected children and adults in Kinshasa, Democratic Republic of Congo. AIDS (London, England). 2015;29(15):2055-2057. 
• Nathan LM, Shi Q, Plewniak K, et al. (2015). Decentralizing Maternity Services to Increase Skilled Attendance at Birth and Antenatal Care Utilization in Rural Rwanda: A Prospective Cohort Study. Maternal and child health journal. 2015;19(9):1949-1955. 
• Adedimeji AA, Hoover DR, Shi Q, et al. (2015). Sexual behavior and risk practices of HIV positive and HIV negative Rwandan women. AIDS and behavior. 2015;19(7):1366-1378.